您好，欢迎访问山东省农业科学院文献资源数据库平台

Investigation and analysis of carbapenem-resistant gram-negative bacterial infection rates across hospitals in Shandong Province in China

文献类型： 外文期刊

作者： Liu, Keke 1 ; Xu, Hua 1 ; Sun, Jian 1 ; Liu, Yuqing 2 ; Li, Weiguang 1 ;

作者机构： 1.Shandong First Med Univ, Shandong Prov Hosp, Dept Infect Control, Jinan, Peoples R China

2.Shandong Acad Agr Sci, Inst Anim Sci & Vet Med, Jinan, Peoples R China

关键词： carbapenem resistance bacteria; detection rate; antibacterial drug use; China; hospital infections

期刊名称：FRONTIERS IN PUBLIC HEALTH （ 影响因子：6.461； 五年影响因子：6.002 ）

ISSN：

年卷期： 2022 年 10 卷

页码：

收录情况： SCI

摘要： BackgroundThe increasing incidence of carbapenem-resistant bacterial infections has become a serious public health threat. This study aimed to investigate and analyze the current regional differences in carbapenem-resistant gram-negative bacteria (CRGN) in a major Province of China, and provide suggestions for preventing hospital infections. MethodsA questionnaire survey was used to obtain the current data on CRGN from 36 hospitals in Shandong Province, China, from 2019 to 2020. The association between the detection rates and discovery rates of CRGN and the use of antibacterial drugs was analyzed using Spearman's correlation coefficient. In addition, we compared the detection rates of CRGN and antibacterial drugs using hospitals categorized according to different levels and economic areas using the Kruskal-Wallis test. ResultsThe average detection rates of CRGN across the 36 hospitals varied from 1.91% to 66.04%. The discovery rate of carbapenem-resistant Enterobacteriaceae (CRE) and carbapenem-resistant Acinetobacter baumannii (CRAB) remained below 5 parts per thousand, and that of carbapenem-resistant Pseudomonas aeruginosa (CRPA) was below 10 parts per thousand. Except for CRAB, the correlations between the detection rate and antimicrobial drug use intensity and carbapenem drug use percentage were 0.11-0.29 and 0.31-0.47, respectively. Carbapenem drug use was higher in the provincial hospital group than in the prefecture-level hospitals (P < 0.05), and that in the high-economic regional hospital group was higher than in the low-economic regional hospital group (P < 0.05). ConclusionsThe detection and discovery rates of CRE were low, and those of CRAB were high in Shandong Province. Larger hospitals have higher carbapenem drug use. These results can be used as a reference for preventing CRGN infections in developing countries and provide a basis for regional carbapenem resistance prevention and control strategies.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：山东省农业科学院文献资源数据库平台

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台