Molecular characterization of three new virulent newcastle disease virus variants isolated in China
文献类型： 外文期刊
作者： Tan, Lei-Tao 1 ; Xu, Huai-Ying 1 ; Wang, You-Ling 1 ; Qin, Zhuo-Ming 1 ; Sun, Lei 2 ; Liu, Wen-Jun 2 ; Cui, Zhi-Zhong 3 ;
作者机构： 1.Shandong Acad Agr Sci, Inst Poultry Sci, Jinan 250100, Peoples R China
2.Chinese Acad Sci, Inst Microbiol, Beijing 100101, Peoples R China
3.Shandong Agr Univ, Coll Anim Sci & Technol, Tai An 271018, Peoples R China
期刊名称：JOURNAL OF CLINICAL MICROBIOLOGY （ 影响因子：5.948； 五年影响因子：5.345 ）
ISSN： 0095-1137
年卷期： 2008 年 46 卷 2 期
页码：
收录情况： SCI
摘要： Three cases of Newcastle disease virus (NDV) found in nature had the lentogenic Motif (112)G-R-Q-G-R-L-117 in their fusion protein cleavage sites. However, both intracerebral pathogenicity and intravenous pathogenicity indexes showed that these NDV isolates were virulent. In comparison with the LaSota live virus vaccine, these viruses had significant genetic variations in the hemagglutinin-neuraminidase gene.
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