您好，欢迎访问山东省农业科学院文献资源数据库平台

Atlas of receptor genes expressed by the bovine morula and corresponding ligand-related genes expressed by uterine endometrium

文献类型： 外文期刊

作者： Sang, Lei 1 ; Xiao, Yao 4 ; Jiang, Zongliang 5 ; Forde, Niamh 6 ; Tian, Xiuchun Cindy 7 ; Lonergan, Patrick 8 ; Hansen 1 ;

作者机构： 1.Fujian Acad Agr Sci, Inst Anim Husb & Vet Med, Fuzhou, Fujian, Peoples R China

2.Univ Florida, DH Barron Reprod & Perinatal Biol Res Program, Dept Anim Sci, Gainesville, FL 32611 USA

3.Univ Florida, Genet Inst, Gainesville, FL 32611 USA

4.Shandong Acad Agr Sci, Inst Anim Sci & Vet Med, Jinan, Shandong, Peoples R China

5.Louisiana State Univ, AgCtr, Sch Anim Sci, Baton Rouge, LA 70803 USA

6.Univ Leeds, Dept Discovery & Translat Sci, Leeds, W Yorkshire, England

7.Univ Connecticut, Dept Anim Sci, Storrs, CT USA

8.Univ Coll, Sch Agr & Food Sci, Dublin, Ireland

关键词： cell signaling; embryo; endometrium; morula; receptors

期刊名称：MOLECULAR REPRODUCTION AND DEVELOPMENT （ 影响因子：2.609； 五年影响因子：3.47 ）

ISSN： 1040-452X

年卷期： 2021 年 88 卷 10 期

页码：

收录情况： SCI

摘要： Regulation of the mammalian embryo involves cell-signaling molecules produced by the maternal oviduct and endometrium. Here, datasets on the transcriptome of the gestational Days 5 and 6 bovine morula and Day 5 maternal endometrium were examined to identify receptor genes expressed by the morula and expression of the corresponding ligand-related genes in the endometrium. A total of 175 receptor genes were identified in the morula, including 48 encoding for growth factors or WNT signaling molecules, 25 for cytokines and chemokines, 35 involved in juxtacrine and matricellular signaling and 25 encoding for receptors for small molecules. Some of the highly-expressed pairs of endometrial ligand and embryo receptor genes included MDK and its receptors ITGB1, SDC4 and LRP2, WNT5A (RYK), VEGFA (ITGB1), GPI (AMFR), and the hedgehog proteins IHH and DHH (HHIP). The most highly expressed receptors for small molecules were GPRC5C (retinoic acid receptor), PGRMC1 (progesterone), and CHRNB2 (acetylcholine). There were also 84 genes encoding for cell signaling ligands expressed by the morula, with the most highly expressed being GPI, AIMP1, TIMP1, IK, and CCN2. The atlas of receptor and ligand genes should prove useful for understanding details of the communication between the embryo and mother that underlies optimal embryonic development.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：山东省农业科学院文献资源数据库平台

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台