您好，欢迎访问山东省农业科学院文献资源数据库平台

Correlation analysis between three novel SNPs of the Src gene in bovine and milk production traits

文献类型： 外文期刊

作者： Liu, Wenyan 1 ; Wang, Ji 1 ; Li, Qiuling 1 ; Ju, Zhihua 1 ; Huang, Jinming 1 ; Wang, Hongmei 1 ; Liu, Shunde 2 ; Li, Jian 1 ;

作者机构： 1.Shandong Acad Agr Sci, Dairy Cattle Res Ctr, Jinan 250100, Shandong, Peoples R China

2.Ningxia Univ, Sch Agr, Ningxia 750021, Peoples R China

关键词： cattle;Src gene;SNP;Milk production traits;Internet resource.

期刊名称：MOLECULAR BIOLOGY REPORTS （ 影响因子：2.316； 五年影响因子：2.357 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： As an essential signaling modulator, Src gene appears to be necessary for increased expression of the prolactin receptor, normal downstream signaling, and alveolar cell organization. In this study, we detected the polymorphism of Src gene by polymerase chain reaction-restriction fragment length polymorphism assay (PCR-RFLP) and DNA sequencing methods in 985 individuals from three Chinese cattle breeds. Three novel single nucleotide polymorphisms (SNPs) (g.14062C>T ss161151834, g.17302G>A ss161151835, g.18107T>C ss161151836) were detected. Least squares analysis showed that cows with g.14062C>T-CC genotypes and g.18107T>C-TT genotypes had the highest protein rate, while the cows with g.17302G>A-GG genotype had higher 305 d milk yield (p < 0.05), fat yield (p < 0.01) and protein yield (p < 0.01) than the ones with genotypes g.17302G>A-GA. These results revealed the statistical significant effects of three SNPs of the Src gene on the milk production traits in Chinese Holstein. In addition, based on the nine genotypes constructed from 27 combined haplotypes, the association analysis between combined haplotypes and milk production traits was carried out. Statistic results showed that the cows with combined haplotypes H2H4(CCGATT) had the highest fat rate and the highest protein rate and the cows with combined haplotypes H1H8(TCGATC) and H3H7(TCGGCC) had greater 305 d mild yield than H1H2(CCAATC)(P < 0.05). Our finding demonstrated that the Src gene possibly contributed to conducting association analysis and can be recognized as genetic marker in milk production traits and other performance for animal breeding and genetics.

  • 相关文献

[1]Novel single nucleotide polymorphisms (SNPs) of the bovine STAT4 gene and their associations with production traits in Chinese Holstein cattle. Zhang, Fenfen,Shi, Fangxiong,Zhang, Fenfen,Huang, Jinming,Li, Qiuling,Ju, Zhihua,Li, Jiangbin,Zhong, Jifeng,Wang, Changfa. 2010

[2]Molecular cloning, promoter analysis, SNP detection of Clusterin gene and their associations with mastitis in Chinese Holstein cows. Wang, Zeying,Wang, Genlin,Huang, Jingmin,Zhong, Jifeng.

[3]Three novel SNPs of the bovine Tf gene in Chinese native cattle and their associations with milk production traits. Ju, Z. H.,Li, Q. L.,Huang, J. M.,Hou, M. H.,Li, R. L.,Li, J. B.,Zhong, J. F.,Wang, C. F.. 2011

[4]The polymorphisms of kappa-casein gene and their associations with milk production traits and expression analysis in Chinese Holstein cattle. Ju, Zhihua,Huang, Jinming,Li, Qiuling,Wang, Hongmei,Zhong, Jifeng,Wang, Changfa. 2011

[5]Single nucleotide polymorphisms, haplotypes and combined genotypes of LAP3 gene in bovine and their association with milk production traits. Zheng, Xue,Ju, Zhihua,Wang, Ji,Li, Qiuling,Huang, Jinming,Zhong, Jifeng,Wang, Changfa,Zheng, Xue,Zhang, Aiwu. 2011

[6]A SNP in intron 8 of CD46 causes a novel transcript associated with mastitis in Holsteins. Wang, Xiuge,Zhong, Jifeng,Gao, Yundong,Ju, Zhihua,Huang, Jinming,Huang, Jinming. 2014

[7]Variants and Gene Expression of the TLR2 Gene and Susceptibility to Mastitis in Cattle. Huang, Jinming,Liu, Li,Wang, Hongmei,Zhang, Cuixia,Ju, Zhihua,Wang, Changfa,Zhong, Jifeng.

[8]Identification of Splice Variants, Targeted MicroRNAs and Functional Single Nucleotide Polymorphisms of the BOLA-DQA2 Gene in Dairy Cattle. Hou, Qinlei,Huang, Jinming,Ju, Zhihua,Li, Qiuling,Li, Liming,Wang, Changfa,Sun, Tao,Wang, Lingling,Hou, Minghai,Zhong, Jifeng,Hang, Suqin.

[9]Genome-wide detection of copy number variations using high-density SNP genotyping platforms in Holsteins. Jiang, Li,Jiang, Jicai,Yang, Jie,Liu, Xuan,Wang, Haifei,Ding, Xiangdong,Liu, Jianfeng,Zhang, Qin,Wang, Jiying. 2013

[10]Genetic mutations potentially cause two novel NCF1 splice variants up-regulated in the mammary gland, blood and neutrophil of cows infected by Escherichia coli. Zhang, Zijing,Guo, Fang,Luo, Guojing,Xu, Yinxue,Wang, Xiuge,Li, Rongling,Ju, Zhihua,Qi, Chao,Zhang, Yan,Li, Qiuling,Wang, Changfa,Zhong, Jifeng,Huang, Jinming.

[11]Exploring genotype-phenotype relationships of the LHX3 gene on growth traits in beef cattle. Huang, Yong-Zhen,Jing, Yong-Jie,Sun, Yu-Jia,Lan, Xian-Yong,Chen, Hong,Zhang, Chun-Lei,Song, En-Liang.

[12]Genetic Variants in SDC3 Gene are Significantly Associated with Growth Traits in Two Chinese Beef Cattle Breeds. Huang, Yong-Zhen,Wang, Qin,Zhang, Chun-Lei,Fang, Xing-Tang,Chen, Hong,Huang, Yong-Zhen,Song, En-Liang.

[13]Effects of Soybean Small Peptides on Rumen Fermentation and on Intestinal and Total Tract Digestion of Luxi Yellow Cattle. Song, E. L.,Liu, X. M.,Wan, F. C.,Wang, W. J.,Yang, W. R.,Wang, W. J.,Song, E. L.,Liu, X. M.,Wan, F. C.,Wang, Y..

[14]Increase in unsaturated fatty acids in membrane lipids of Suaeda salsa L. enhances protection of photosystem II under high salinity. Sui, N.,Li, K.,Song, J.,Wang, B. -S.,Li, M..

[15]Two enzymatic sources of nitric oxide in different organs of apple plant. Gao, H. J.,Wang, J. Y.,Wang, J. X.,Yang, H. Q.,Yang, H. Q..

[16]花生杂种分子鉴定和ahFAD2基因分型技术研究进展. 袁美,王传堂,韩锁义,任艳,尹亮,石延茂,徐平,王效华,李双铃,郑奕雄. 2017

[17]INCENP基因功能性单倍型可调控启动子活性并影响公牛精液品质. 刘娟,孙艳,姜强,杨春红,黄金明,李建斌,侯明海,仲跻峰,王长法. 2016

[18]利用特异性SNP位点鉴定花生杂交F_1代真假杂种. 韩燕,马登超,刘译阳,崔凤,孙秀芹,李荣冲,万书波,李国卫. 2016

[19]牛MC1R基因——新的SNP. 甘海云,张秀红,李景鹏. 2007

[20]MC1R基因多态性与杜黑猪毛色关系研究. 巩静,杨晴,王艺盼,王彦平,朱晓东,张传生,耿立英,王继英. 2023

作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：山东省农业科学院文献资源数据库平台

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台