文献类型： 外文期刊

作者： Gangurde, Sunil S. ¹ ; Xavier, Alencar ³ ; Naik, Yogesh Dashrath ⁴ ; Jha, Uday Chand ⁵ ; Rangari, Sagar Krushnaji ⁴ ; Kumar, Raj ⁴ ; Reddy, M. S. Sai ⁴ ; Channale, Sonal ⁶ ; Elango, Dinakaran ⁷ ; Mir, Reyazul Rouf ⁸ ; Zwart, Rebecca ⁶ ; Laxuman, C. ⁹ ; Sudini, Hari Kishan ¹⁰ ; Pandey, Manish K. ⁶ ; Punnuri, Somashekhar ¹¹ ; Mendu, Venugopal ¹² ; Reddy, Umesh K. ¹³ ; Guo, Baozhu ¹ ; Gangarao, N. V. P. R. ¹⁴ ; Sharma, Vinay K. ⁴ ; Wang, Xingjun ¹⁵ ; Zhao, Chuanzhi ¹⁵ ; Thudi, Mahendar ⁴ ;

作者机构： 1.united States Dept Agr, USDA Agr Res Serv ARS, Crop Genet & Breeding Res, Tifton, GA USA

2.Univ Georgia, Dept Plant Pathol, Tifton, GA USA

3.Purdue Univ, Dept Agron, W Lafayette, IN USA

4.Dr Rajendra Prasad Cent Agr Univ RPCAU, Bihar, India

5.Indian Inst Pulses Res IIPR, Indian Council Agr Res ICAR, Kanpur, Uttar Pradesh, India

6.Univ Southern Queensland USQ, Crop Hlth Ctr, Toowoomba, Qld, Australia

7.Iowa State Univ, Dept Agron, Ames, IA USA

8.Sher Ekashmir Univ Agr Sci & Technol SKUAST, Fac Agr, Sopore, India

9.Univ Agr Sci, Zonal Agr Res Stn ZARS, Kalaburagi, Raichur, Karnataka, India

10.Int Crops Res Inst Semi Arid Trop, Hyderabad, Telangana, India

11.Dr Ft Valley State Univ, Coll Agr Family Sci & Technol, Ft Valley, GA USA

12.Montana State Univ, Dept Plant Sci & Plant Pathol, Bozeman, MT USA

13.West Virginia State Univ, Dept Biol, West Virginia, WV USA

14.Int Maize & Wheat Improvement Ctr CIMMYT, Nairobi, Kenya

15.Shandong Acad Agr Sci, Inst Crop Germplasm Resources, SAAS, Jinan, Peoples R China

关键词： plant diseases; genome wide association studies; haplotypes; pangenomes; multi-parent populations; k-mers

期刊名称：FRONTIERS IN PLANT SCIENCE （ 影响因子：6.627； 五年影响因子：7.255 ）

ISSN： 1664-462X

年卷期： 2022 年 13 卷

页码：

收录情况： SCI

摘要： Climate change across the globe has an impact on the occurrence, prevalence, and severity of plant diseases. About 30% of yield losses in major crops are due to plant diseases; emerging diseases are likely to worsen the sustainable production in the coming years. Plant diseases have led to increased hunger and mass migration of human populations in the past, thus a serious threat to global food security. Equipping the modern varieties/hybrids with enhanced genetic resistance is the most economic, sustainable and environmentally friendly solution. Plant geneticists have done tremendous work in identifying stable resistance in primary genepools and many times other than primary genepools to breed resistant varieties in different major crops. Over the last two decades, the availability of crop and pathogen genomes due to advances in next generation sequencing technologies improved our understanding of trait genetics using different approaches. Genome-wide association studies have been effectively used to identify candidate genes and map loci associated with different diseases in crop plants. In this review, we highlight successful examples for the discovery of resistance genes to many important diseases. In addition, major developments in association studies, statistical models and bioinformatic tools that improve the power, resolution and the efficiency of identifying marker-trait associations. Overall this review provides comprehensive insights into the two decades of advances in GWAS studies and discusses the challenges and opportunities this research area provides for breeding resistant varieties.