文献类型： 外文期刊
作者： Liu, Chao 1 ; Sun, Hui 3 ; Wang, Wei-Ting 1 ; Zhang, Jin-Bao 4 ; Cheng, An-Wei 1 ; Guo, Xu 1 ; Sun, Jin-Yue 1 ;
作者机构： 1.Shandong Acad Agr Sci, Inst Agrofood Sci & Technol, Jinan, Peoples R China
2.Key Lab Agroprod Proc Technol Shandong Prov, Jinan, Peoples R China
3.Shandong Chengchuang Pharmaceut R&D Co Ltd, Jinan, Peoples R China
4.Weifang Med Univ, Dept Genet, Weifang, Peoples R China
关键词： Gleditsia sinensis;triterpenoid saponin;antiproliferative
期刊名称：NATURAL PRODUCT RESEARCH （ 影响因子：2.861； 五年影响因子：2.572 ）
ISSN：
年卷期：
页码：
收录情况： SCI
摘要： Chemical investigation of the anomalous fruits of Gleditsia sinensis led to the isolation and identification of a new triterpenoid saponin, 3-O-beta-D-xylopyranosyl-(1 -> 2)-alpha-L-arabinopyranosyl-(1 -> 6)-beta-D-glucopyranosyl oleanolic acid 28-O-beta-D-xylopyranosyl-(1 -> 4)-alpha-L-rhamnopyrano--syl-(1 -> 4)-beta-D-xylopyranosyl-(1 -> 4)-alpha-L-rhamnopyranosyl-(1 -> 3)-beta-D-glucopyranosyl ester (1), along with other nine known compounds (2-10). All the isolates from this species were reported for the first time. The structure of Compound 1 was determined by a detailed analysis using various analytical techniques, including 1D and 2D NMR. In vitro antiproliferative activities of Compound 1 on MCF-7 and Hep-G2 tumor cell lines were evaluated. IC50 values against the two cell lines were 9.5 and 11.6M, respectively.
- 相关文献
作者其他论文 更多>>
-
MUP1 mediates urolithin A alleviation of chronic alcohol-related liver disease via gut-microbiota-liver axis
作者：Zhang, Hongbo;Li, Chaoyue;Han, Lin;Xiao, Yao;Liu, Zhigang;Wang, Min;Bian, Ji;Liu, Chao;Gong, Lan
关键词：Alcohol-related liver disease; urolithin A; endoplasmic reticulum stress; MUP1 protein; gut-microbiota-liver axis
-
The molecular mechanism of action for the potent antitumor component extracted using supercritical fluid extraction from Croton crassifolius root
作者：Guo, Xu;Zhang, Rui-Rui;Sun, Jin-Yue;Chen, Ying-Ying;Sun, Hui;Liu, Chao;Liu, Yan;Yuan, Xian-Shun
关键词：Anti-proliferative; Apoptosis induction; Molecular mechanism; Croton crassifolius
-
Nutrition and flavor analysis of Spirulina through co-fermentation with Lactobacillus acidophilus and Kluyveromyces marxianus and its effect on attenuating metabolic associated fatty liver disease
作者：Yu, Jinhui;Liu, Chao;Liu, Yuanyuan;Ma, Deyuan;Chen, Gao;Han, Fuwen;You, Shengbo;Bi, Yuping;Wu, Yingjie;Yu, Jinhui;Ma, Deyuan;Chen, Gao;You, Shengbo;Bi, Yuping;Liu, Chao;Wang, Mingjie;Wang, Mingjie;Liu, Yuanyuan;Ran, Liyuan;Yu, Zichao;Wu, Yingjie
关键词：Spirulina; Lactobacillus acidophilus; Kluyveromyces marxianus; Co -fermentation; MAFLD
-
Preparation of emulsions-filled sodium alginate hydrogel beads to enhance the anti-cancer activity of fangchinoline in vivo and in vitro
作者：Liu, Chao;Wang, Mu-Xuan;Lyu, Xu-Tao;Guo, Xu;Sun, Jin-Yue;Lu, Chao-Xia;Li, Ning-Yang;Zhang, Kai;Prieto, M. A.
关键词：Fangchinoline; Emulsions; Hydrogel beads; Anti-cancer; Molecular mechanism
-
Evaluating the hypolipidemic effect of garlic essential oil encapsulated in a novel double-layer delivery system
作者：Zhang, Xueli;Tang, Xiaozhen;Zhang, Xueli;Guo, Xu;Sun, Jinyue;Chen, Yingying;Zhang, Mengqi;Wang, Wenliang;Liu, Chao;Li, Ningyang;Simal-Gandara, Jesus;Xu, Huiying
关键词：Garlic essential oil; Cyclodextrin inclusion complex liposome; delivery system; Characterization; Stability; Lowering blood lipid
-
Effect of immune checkpoint inhibitors at different treatment time periods on prognosis of patients with extensive-stage small-cell lung cancer
作者：Mi, Song;Zhang, Jiandong;Mi, Song;Liu, Xin;Liang, Ning;Hu, Pingping;Zhang, Jiandong;Mi, Song;Liu, Xin;Liang, Ning;Hu, Pingping;Zhang, Jiandong;Yang, Yunxin;Tang, Shaotong;Sun, Jinyue;Liu, Chao;Ren, Qidong;Lu, Jihong
关键词：Extensive-stage small-cell lung cancer (ES-SCLC); Immunotherapy; Prognostication; Lines of treatment
-
Extraction, purification and anticancer activity studies on triterpenes from pomegranate peel
作者：Zhang, Mengqi;Zhang, Yutao;Guo, Xu;Chen, Yingying;Sun, Shutao;Ren, Qidong;Sun, Jinyue;Liu, Chao;Zhang, Mengqi;Zhang, Yutao;Li, Ningyang;Li, Huimin;Zhou, Guihua;Simal-Gandara, Jesus;Li, Ningyang
关键词：
