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Antioxidant and hepatoprotective activities of intracellular polysaccharide from Pleurotus eryngii SI-04

文献类型： 外文期刊

作者： Zhang, Chen 1 ; Li, Shangshang 1 ; Zhang, Jianjun 1 ; Hu, Chunlong 2 ; Che, Gen 3 ; Zhou, Meng 4 ; Jia, Le 1 ;

作者机构： 1.Shandong Agr Univ, Coll Life Sci, Tai An 271018, Shandong, Peoples R China

2.Shandong Agr Univ, Coll Forestry, Tai An 271018, Shandong, Peoples R China

3.Shandong Acad Agr Sci, Jinan 250100, Peoples R China

4.Qual & Safety Monitoring Ctr Anim Prod, Jinan 250002, Peoples R China

关键词： Intracellular polysaccharide;Pleurotus eryngii SI-04;Antioxidant and hepatoprotective activity

期刊名称：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES （ 影响因子：6.953； 五年影响因子：6.737 ）

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收录情况： SCI

摘要： In present study, the intracellular polysaccharide (IPS) and its two fractions of IPS-1 and IPS-2 were obtained and purified by DEAE-52 cellulose chromatography from Pleurotus eryngii SI-04 mycelia, and their hepatoprotective effects were also investigated. The results showed that the IPS-2 had superior hepatoprotective effects by increasing the serum enzyme activities and bilirubin (BIL) levels, decreasing the serum albumin (ALB) and triglyceride (TG) levels, improving the hepatic antioxidant status, and ameliorating the hepatic structure damage. Furthermore, the monosaccharide composition and main bond types were also analyzed. These conclusions demonstrated that the both IPS and its fractions might be suitable for functional foods and natural drugs in preventing the acute liver damage. (C) 2016 Elsevier B.V. All rights reserved.

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[1]Antihyperlipidaemic and hepatoprotective activities of acidic and enzymatic hydrolysis exopolysaccharides from Pleurotus eryngii SI-04. Gong, Zhiyuan,Zhang, Chen,Song, Xingling,Zhang, Jianjun,Jia, Le,Li, Juan,Wang, Jing,Wu, Shang,Hu, Chunlong. 2017

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