Chemical constituents, anticancer, antimicrobial and antioxidant activities of essential oil from Anaphalis lacteal grown in Qinghai-Tibet Plateau
文献类型： 外文期刊
作者： Liu, Shi-Jun 1 ; Liao, Zhi-Xin 1 ; Liu, Chao 1 ; Sun, Jin-Yue 3 ;
作者机构： 1.Southeast Univ, Sch Chem & Chem Engn, Dept Pharmaceut Engn, Nanjing 211189, Jiangsu, Peoples R China
2.Southeast Univ, Jiangsu Prov Hitech Key Lab Biomed Res, Nanjing 211189, Jiangsu, Peoples R China
3.Shandong Acad Agr Sci, Inst Agrofood Sci & Technol, Jinan 250100, Peoples R China
关键词： Anaphalis lacteal;compositae;chemical constituents;anticancer;antimicrobial;antioxidant activities
期刊名称：NATURAL PRODUCT RESEARCH （ 影响因子：2.861； 五年影响因子：2.572 ）
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收录情况： SCI
摘要： The chemical constituent of the essential oil from Anaphalis lacteal was determined; 31 compounds, representing 93.91 % of the total oil, were identified by gas chromatography-mass spectrometry analysis. Three Gram-positive bacteria species, three Gram-negative bacteria species and four fungi were used to determine antimicrobial activity; the results revealed that the essential oil had a remarkable antimicrobial effect against bacteria and a susceptive effect against fungus. The oil also possessed more efficient free-radical scavenging activities than butylated hydroxytoluene (BHT) with 50% inhibitory concentration (IC_(50)) value 31 mug/mL (40muLg/mL for BHT). MTT assay illustrated that the oil expressed certain effect in inhibiting the growth of HeLa and Hep-6 cancer cells.
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