Green and Facile Synthesis and Antioxidant and Antibacterial Evaluation of Dietary Myricetin-Mediated Silver Nanoparticles
文献类型： 外文期刊
作者： Li, Zhao 1 ; Ma, Wenya 1 ; Ali, Iftikhar 1 ; Zhao, Huanzhu 1 ; Wang, Daijie 1 ; Qiu, Jiying 3 ;
作者机构： 1.Shandong Acad Sci, Sch Pharmaceut Sci, Shandong Anal & Test Ctr, Jinan 250014, Peoples R China
2.Shandong Acad Sci, Key Lab Appl Technol Sophisticated Analyt Instrum, Shandong Anal & Test Ctr, Jinan 250014, Peoples R China
3.Shandong Acad Agr Sci, Inst Agrofood Sci & Technol, Jinan 250100, Peoples R China
期刊名称：ACS OMEGA （ 影响因子：3.512； 五年影响因子：3.613 ）
ISSN： 2470-1343
年卷期： 2020 年 5 卷 50 期
页码：
收录情况： SCI
摘要： Myricetin (MY) is a dietary flavonoid which exhibits a wide spectrum of biological properties, viz., antibacterial, antioxidant, anticancer, and so forth. The lower solubility in aqueous medium and hence lesser bioavailability of MY limits the use of such dietary flavonoids in further in vivo research. To overcome bioavailability limitations, a number of drug-delivery systems are being investigated. Herein, MY-mediated silver nanoparticles (MY-AgNPs) were synthesized by a green approach to improve the therapeutic efficacy of MY. MY-AgNPs were characterized by ultraviolet-visible spectroscopy (UV-Vis), scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier transform infrared (FTIR) spectroscopy, and X-ray powder diffraction (XRD). The results showed that the dispersion of AgNPs had the maximum UV-vis absorption at about 410 nm. The synthesized nanoparticles were almost spherical. MY-AgNPs were further investigated against human pathogenic bacteria, and their antioxidant potential was also determined. The free radical scavenging rate was about 60-87%. MY-AgNPs had good antibacterial activity against Escherichia coli and Salmonella at room temperature with minimum inhibitory concentrations of 10(-4) and 10(-5) g/L, respectively.
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