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Genetic and biological characterizations of a Newcastle disease virus from swine in china

文献类型： 外文期刊

作者： Yuan, Xiaoyuan 1 ; Wang, Youling 2 ; Yang, Jinxing 2 ; Xu, Huaiying 2 ; Zhang, Yuxia 2 ; Qin, Zhuoming 2 ; Ai, Hongbin 1 ;

作者机构： 1.Shandong Normal Univ, Coll Life Sci, Jinan 250014, Peoples R China

2.Shandong Acad Agr Sci, Jinan 250023, Peoples R China

关键词： NDV;Swine;Genetic and biological characterizations;F gene

期刊名称：VIROLOGY JOURNAL （ 影响因子：4.099； 五年影响因子：3.719 ）

ISSN： 1743-422X

年卷期： 2012 年 9 卷

页码：

收录情况： SCI

摘要： Background: Newcastle Disease Virus (NDV) has been considered to only infect avian species. However, one paramyxovirus named as Xiny10 was isolated from swine. The differences of Xiny10, another previous swine NDV (JL01) and vaccine strain La Sota were compared on the basis of sequences of the whole-lengthen Fusion (F) gene and biological characteristics. Findings: Through serologic tests and sequence alignment, Xiny10 was proved as NDV. It has great differences with JL01 in virulence, biological characteristics, genotype and amino acid homology of F gene. The sequence alignment showed Xiny10 and La Sota both belonged to genotype II. It shared 97.3% to 98.7% identities with genotype II NDVs, which was higher than these strains from the other genotypes. Conclusions: These above data suggested that the swine virus was NDV and it might be generated from La Sota.

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