文献类型: 外文期刊
作者: Lin, Haichao 1 ; Wang, Huaizhong 1 ; Wang, Yanping 1 ; Liu, Chang 1 ; Wang, Cheng 1 ; Guo, Jianfeng 1 ;
作者机构: 1.Shandong Acad Agr Sci, Inst Anim Sci & Vet Med, Jinan 250100, Peoples R China
2.Key Lab Dis Control & Anim Breeding Shandong Prov, Jinan 250100, Peoples R China
关键词: embryo implantation;endometrium;pigs;pregnancy;sows;transcriptome
期刊名称:GENES ( 影响因子:4.096; 五年影响因子:4.339 )
ISSN: 2073-4425
年卷期: 2015 年 6 卷 4 期
页码:
收录情况: SCI
摘要: In pigs, successful embryo implantation is an important guarantee for producing litter size, and early embryonic loss occurring on day 12-30 of gestation critically affects the potential litter size. The implantation process is regulated by the expression of numerous genes, so comprehensive analysis of the endometrium is necessary. In this study, RNA sequencing (RNA-Seq) technology is used to analyze endometrial tissues during early pregnancy. We investigated the changes of gene expression between three stages (day 12, 18, and 25) by multiple comparisons. There were 1557, 8951, and 2345 differentially expressed genes (DEGs) revealed between the different periods of implantation. We selected several genes for validation by the use of quantitative real-time RT-PCR. Bioinformatic analysis of differentially expressed genes in the endometrium revealed a number of biological processes and pathways potentially involved in embryo implantation in the pig, most noticeably cell proliferation, regulation of immune response, interaction of cytokine-cytokine receptors, and cell adhesion. These results showed that specific gene expression patterns reflect the different functions of the endometrium in three stages (maternal recognition, conceptus attachment, and embryo implantation). This study identified comprehensive transcriptomic profile in the porcine endometrium and thus could be a foundation for targeted studies of genes and pathways potentially involved in abnormal endometrial receptivity and embryo loss in early pregnancy.
- 相关文献
作者其他论文 更多>>
-
Effects of Substitute Substrate, Water, and Fertilizer Management on the Growth of Potted Chrysanthemums
作者:Lu, Yufan;Zhou, Tongjun;Guo, Jinqing;Zhong, Jian;Li, Dawei;Shi, Huajin;Liu, Chang;Xiang, Ruizi;Sun, Ming;Guo, Jinqing
关键词:potted chrysanthemum; substitute substrates; fertilizers; water
-
Analysis of genetic variations of a recombinant strain derived from the three lineages of porcine reproductive and respiratory syndrome virus-2
作者:Zheng, Limei;Ma, Yingru;Wen, Jianxin;Li, Jun;Han, Xianjie;Wu, Xiaoyan;Liu, Chang;Li, Chen;Shi, Jianli;Han, Hong;Xu, Shaojian;Hrabchenko, Nataliia;Li, Jun;Huang, Mengjie;Qiu, Jianhua
关键词:PRRSV; recombination strains; GP5; NSP2; genetic evolutionary analysis; next-generation sequencing
-
Optimized production of full-length PCV2d virus-like particles in Escherichia coli : A cost-effective and high-yield approach for potential vaccine antigen development
作者:Zhang, Chengxin;He, Fang;Li, Nianfeng;Wen, Jianxin;Han, Xianjie;Li, Jun;Wu, Xiaoyan;Shi, Jianli;Li, Chen;Liu, Chang;Xu, Shaojian;Han, Hong;Hrabchenko, Nataliia;Du, Wei;Li, Jun
关键词:PCV2d; Cap protein; Virus -like particles (VLPs); Escherichia coli expression system; Vaccine development; Immunogenicity
-
Formic acid enhances whole-plant mulberry silage fermentation by boosting lactic acid production and inhibiting harmful bacteria
作者:Hao, Lihong;Jiang, Fugui;Wang, Yanping;Wang, Huaizhong;Hu, Hongmei;You, Wei;Hu, Xin;Cheng, Haijian;Wang, Cheng;Song, Enliang;Hao, Lihong;Jiang, Fugui;Wang, Yanping;Wang, Huaizhong;Hu, Hongmei;You, Wei;Hu, Xin;Cheng, Haijian;Wang, Cheng;Song, Enliang;Song, Enliang
关键词:mulberry; silage; glucose; formic acid; lactic acid bacteria; salts; bacterial community
-
Comparative Analysis of Intestinal Inflammation and Microbiota Dysbiosis of LPS-Challenged Piglets between Different Breeds
作者:Li, Chao;Wang, Yanping;Zhao, Xueyan;Li, Jingxuan;Wang, Huaizhong;Ren, Yifan;Wang, Jiying;Li, Chao;Wang, Yanping;Zhao, Xueyan;Li, Jingxuan;Wang, Huaizhong;Ren, Yifan;Wang, Jiying;Li, Chao;Song, Qinye;Sun, Houwei;Zhu, Xiaodong
关键词:Heigai pigs; intestinal inflammation; jejunum microbiota; lipopolysaccharide; post-weaning diarrhea; 16S rDNA-Seq
-
Dietary addition of Humulus scandens improved the intestinal barrier in rabbits
作者:Liu, Gongyan;Hao, Lihong;Wang, Cheng;Zhang, Yin;Sun, Haitao;Hu, Hongmei;Liu, Gongyan;Hao, Lihong;Wang, Cheng;Zhang, Yin;Sun, Haitao;Hu, Hongmei;Sun, Haitao;Hu, Hongmei
关键词:Humulus scandens; intestinal barrier; rabbits; production performance
-
Comparative Analysis of Structural Composition and Function of Intestinal Microbiota between Chinese Indigenous Laiwu Pigs and Commercial DLY Pigs
作者:Li, Chao;Song, Qinye;Li, Chao;Zhao, Xueyan;Wang, Yanping;Ren, Yifan;Li, Jingxuan;Wang, Huaizhong;Wang, Jiying;Li, Chao;Zhao, Xueyan;Wang, Yanping;Ren, Yifan;Li, Jingxuan;Wang, Huaizhong;Wang, Jiying;Zhao, Guisheng;Xue, Haipeng
关键词:intestinal microbiota; 16S rRNA sequencing; Laiwu pigs; DLY pigs



