文献类型： 外文期刊

作者： Rajalakshmi, Kanagaraj ¹ ; Muthusamy, Selvaraj ¹ ; Lee, Ho-Jin ³ ; Kannan, Palanisamy ² ; Zhu, Dongwei ⁴ ; Lodi, Rathna Silviya ⁵ ; Xie, Meng ¹ ; Xie, Jimin ¹ ; Song, Jong-Won ⁶ ; Xu, Yuanguo ¹ ;

作者机构： 1.Jiangsu Univ, Sch Pharm, Sch Chem & Chem Engn, Zhenjiang 212013, Peoples R China

2.Jiaxing Univ, Coll Biol Chem Sci & Engn, Jiaxing 314001, Zhejiang, Peoples R China

3.Southwest Tennessee Community Coll, Dept Nat Sci, Memphis, TN 38134 USA

4.Jiangsu Univ, Affiliated Peoples Hosp, Sch Med, Dept Lab Med, Zhenjiang 212013, Peoples R China

5.Shandong Acad Agr Sci, Jinan, Peoples R China

6.Daegu Univ, Dept Chem Educ, Daegudae Ro 201, Gyongsan 38453, Gyeongsangbuk D, South Korea

关键词： Quinoline-2; 4-dintrobenzoate; Nucleophilic substitution; Intramolecular charge transfer; Soil samples; Isoniazid-hydrazine

期刊名称：SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY （ 影响因子：4.4； 五年影响因子：3.9 ）

ISSN： 1386-1425

年卷期： 2024 年 304 卷

页码：

收录情况： SCI

摘要： Substitution can be employed to competently tune the photophysical properties of chemosensors. The effect of substituents on the absorption and emission properties of quinoline probes was investigated. Therefore, salicylaldehyde (S), N-diethylamino-salicylaldehyde (D), and nitro-salicylaldehyde (W)-based quinoline Schiff base derivatives were investigated with hydrazine and studied for their photophysical properties. The nucleophilic substitution reaction was used as a sensing mechanism between the probes and hydrazine and investigated with 1H NMR, HR-MS characterizations, and DFT calculations. The sensitivity of QW-R is greater than that of QS-R and QD-R because of the stronger intramolecular charge transfer (ICT) in QW-R. The calculated LOD values are 28 nM for QS-R, 30 nM for QD-R, and 9 nM for QW-R. The probes were employed to monitor gaseous hydrazine using a smartphone and analyze solution forms of hydrazine in soil, water, and food samples, and living cells. Moreover, the in situ hydrazine release was monitored with bioimaging by administering an isoniazid drug. Significantly, the electronic effect of substituents over fluorescence showing, ranging from electron-donating to electron-withdrawing was investigated. We anticipate that this approach may be a promising strategy for the rational design of fluorescent sensors.