Detection of the 23-bp nucleotide sequence mutation in retinoid acid receptor related orphan receptor alpha(RORA)gene and its effect on sheep litter size
文献类型： 外文期刊
作者： Yang, Yuta 1 ; Hu, Huina 1 ; Mao, Cui 2 ; Jiang, Fugui 3 ; Lu, Xiaofang 2 ; Han, Xufei 2 ; Hao, Kunjie 2 ; Lan, Xianyong; 1 ;
作者机构： 1.Northwest A&F Univ, Coll Anim Sci & Technol, 22 Xinong Rd, Yangling 712100, Shaanxi, Peoples R China
2.Tianjin Aoqun Anim Husb Co Ltd, Tianjin Aoqun Sheep Ind Res Inst, Tianjin 301607, Peoples R China
3.Shandong Acad Agr Sci, Inst Anim Sci & Vet Med, Shandong Key Lab Anim Dis Control & Breeding, Jinan, Peoples R China
关键词： Sheep; retinoid acid receptor related orphan receptor alpha (RORA); Insertion; deletion (Indel); mutation; litter size
期刊名称：ANIMAL BIOTECHNOLOGY （ 影响因子：2.282； 五年影响因子：1.702 ）
ISSN： 1049-5398
年卷期：
页码：
收录情况： SCI
摘要： Retinoid acid receptor related orphan receptor alpha (RORA) transcribes steroid-related genes to regulate estrogen synthesis. As an important reproductive trait, litter size relates to estrogen synthesis. Therefore, it is important to investigate the association betweenRORAgene and sheep litter size. In this study, one 23-bp nucleotide sequence mutation was identified in intron 1 ofRORAgene in 532 female Australian White Sheep. Moreover, the polymorphic information content (PIC) values of this locus was 0.219. The litter size of ID genotype was significantly better than II genotype and DD genotype in the second born litter size (p < 0.05). This loci was related to third born litter size and the ID is the dominant genotype (p < 0.05). The association between combined genotypes and average litter size showed that sheep with heterozygote (ID) genotypes had larger lamb than homozygous (DD and II) genotypes. To sum, this study provided theoretical references for the comprehensively research of the function ofRORAgene and the breeding of Australian White Sheep. The 23-bp indel variants could be considered as molecular markers for the second and third born litter size of sheep for MAS breeding.
- 相关文献
作者其他论文 更多>>
-
Are two beneficial mutations (p.Q249R and 90-bp Indel) within the ovine BMPRIB gene associated with growth traits?
作者：Xu, Hongwei;Akhmet, Nazar;Luo, Yunyun;Pan, Chuanying;Akhatayeva, Zhanerke;Lan, Xianyong;Guo, Zhenggang;Song, Enliang;Malmakov, Nurlan;Akhatayeva, Zhanerke
关键词：sheep; FecB (BMPRIB); polymorphism; growth traits; MAS
-
Formic acid enhances whole-plant mulberry silage fermentation by boosting lactic acid production and inhibiting harmful bacteria
作者：Hao, Lihong;Jiang, Fugui;Wang, Yanping;Wang, Huaizhong;Hu, Hongmei;You, Wei;Hu, Xin;Cheng, Haijian;Wang, Cheng;Song, Enliang;Hao, Lihong;Jiang, Fugui;Wang, Yanping;Wang, Huaizhong;Hu, Hongmei;You, Wei;Hu, Xin;Cheng, Haijian;Wang, Cheng;Song, Enliang;Song, Enliang
关键词：mulberry; silage; glucose; formic acid; lactic acid bacteria; salts; bacterial community
-
Effect of Dietary Supplementation of Astragaloside IV on Growth performance, Inflammatory, and Antioxidant Status of Holstein Male Calves
作者：Wang, Yafang;Song, Enliang;Wang, Yafang;Jiang, Fugui;Cheng, Haijian;Liu, Yifan;Wei, Chen;Liu, Ce;Song, Enliang;Wang, Yafang;Jiang, Fugui;Cheng, Haijian;Liu, Yifan;Wei, Chen;Liu, Ce;Song, Enliang
关键词：Astragaloside IV; Growth performance; Antioxidant; Inflammatory; Holstein calves
-
Insertion/Deletion (InDel) Variants within the Sheep Fat-Deposition-Related PDGFD Gene Strongly Affect Morphological Traits
作者：Luo, Yunyun;Zhang, Mengyang;Guo, Zhengang;Wijayanti, Dwi;Lan, Xianyong;Guo, Zhengang;Xu, Hongwei;Jiang, Fugui
关键词：sheep; PDGFD gene; insertion/deletion (InDel); morphological traits; association
-
The ovine HIAT1 gene: mRNA expression, InDel mutations, and growth trait associations
作者：Luo, Yunyun;Akhatayeva, Zhanerke;Mao, Cui;Lan, Xianyong;Mao, Cui;Jiang, Fugui;Guo, Zhengang;Xu, Hongwei
关键词：sheep; HIAT1 gene; insertion; deletion (InDel); growth traits; marker-assisted selection (MAS)
-
Bovine HOXA11 Gene Identified from RNA-Seq: mRNA Profile Analysis and Genetic Variation Detection Using ME Method and Their Associations with Carcass Traits
作者：Huang, Yangming;Zhang, Kejing;Li, Yafang;Zhang, Sihuan;Akhatayeva, Zhanerke;Lan, Xianyong;Zhang, Sihuan;Jiang, Fugui;Song, Enliang
关键词：cattle; HOXA11; insertion; deletion (InDel); mathematical expectation (ME); carcass traits; marker-assisted selection (MAS)
-
A 14-bp deletion in bovine EPAS1 gene is associated with carcass traits
作者：Jiang, Enhui;Wang, Hongyang;Li, Xuelan;Bi, Yi;Mao, Cui;Lan, Xianyong;Jiang, Fugui;Song, Enliang;Lan, Xianyong;Song, Enliang
关键词：EPAS1; cattle; carcass traits; polymorphism; association
