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Genetic analysis of porcine circovirus type 2 from dead minks

文献类型： 外文期刊

作者： Wang, Gui-sheng 1 ; Sun, Na 3 ; Tian, Fu-lin 2 ; Wen, Yong-jun 3 ; Xu, Cong 2 ; Li, Jun 4 ; Chen, Qiang 5 ; Wang, Jin-bao 1 ;

作者机构： 1.Shandong Univ, Sch Life Sci, Jinan, Peoples R China

2.Shandong Prov Ctr Anim Dis Control & Prevent, Jinan, Peoples R China

3.Chinese Acad Agr Sci, Inst Special Econ Anim & Plants, Changchun, Peoples R China

4.Shandong Acad Agr Sci, Inst Anim Sci & Vet Med, Shandong Key Lab Anim Dis Control & Breeding, Jinan, Peoples R China

5.JL Te Yan Biol Technol Ltd Liabil Co, Changchun, Peoples R China

期刊名称：JOURNAL OF GENERAL VIROLOGY （ 影响因子：3.891； 五年影响因子：3.719 ）

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收录情况： SCI

摘要： Circovirus infection is a growing problem in the field of veterinary and public health. It is associated with enteric diseases in both mammalian and avian hosts. In this study, we detected and isolated porcine circovirus strains in the tissue samples of minks that died from diarrhoea in Shandong Province, China. We sequenced the whole genome of two porcine strains of Circovirus, designated as MiSD-1 and MiSD-2, which had a 97.34% similarity on nucleotide sequence and were closely related to porcine circovirus type 2 (PCV2), but distantly related to mink circoviral species. Phylogenetically MiSD-1 and MiSD-2 are a part of the PCV2b genotype cluster, which is a highly prevalent genotype worldwide. The closer relationship of MiSD-1 and MiSD-2 to PCV2 from pigs than to other mink circoviral species may be evidence of crossspecies transmission and considerable zoonotic potential.

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