文献类型： 外文期刊
作者： Fan, Lixia 1 ; Ji, Zhiqin 1 ; Guo, Zhengyan 2 ; Wu, Wenjun 1 ;
作者机构： 1.Northwest A&F Univ, State Key Lab Crop Stress Biol Arid Areas, Yangling 712100, Shaanxi, Peoples R China
2.Chinese Acad Sci, Inst Microbiol, State Key Lab Microbial Resources, Beijing 100101, Peoples R China
3.Shandong Acad Agr Sci, Inst Qual Stand & Testing Technol Agroprod, Shandong Prov Key Lab Test Technol Food Qual & Sa, Jinan 250100, Peoples R China
关键词： NVV-G12;desertomycin A;antibacterial activities;Streptomyces alboflavus 313
期刊名称：CHEMISTRY OF NATURAL COMPOUNDS （ 影响因子：0.809； 五年影响因子：0.708 ）
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收录情况： SCI
摘要： In our continuous investigation of metabolites of Streptomyces alboflavus 313, NW-G12 (1), a novel nonchlorinated analogue of NW-G01, was obtained as a trace constituent in the weak polarity part and a known desertomycin A (2) was also isolated from the fermentation broth in the strong polarity part. The structures of compounds 1 and 2 were established by comprehensive analysis of 1D and 2D NMR spectral data. Moreover, compounds 1 and 2 showed strong antibacterial activities against Bacillus cereus. Staphylococcus aureus, and Bacillus subtilis, with MICs of less than 10 μg/mL, but both show no antibacterial activities against two test gram-negative bacteria.
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