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Correlation of Antibody Levels with Peripheral Lymphocyte Subsets and Routine Hematological Parameters after Vaccination with FMD Vaccine in Young Sires

文献类型： 外文期刊

作者： Yang, Ling 1 ; He, Kaili 1 ; Li, Jianbin 2 ; Ma, Yabin 4 ; Li, Rongling 2 ; Hou, Minghai 2 ; Gao, Yundong 2 ; Zhong, Jife 1 ;

作者机构： 1.Hebei Univ Engn, Coll Life Sci & Food Engn, Dept Anim Sci, Handan 056021, Peoples R China

2.Shandong Acad Agr Sci, Dairy Cattle Res Ctr, Jinan 250100, Shandong, Peoples R China

3.Huayu Agr Sci & Technol Co Ltd, Handan 057153, Peoples R China

4.Hebei Stn Livestock Improvement, Shijiazhuang 050011, Hebei, Peoples R China

关键词： Antibody level; Foot and mouth disease; Routine hematological parameter; T-cell subset; Young sire

期刊名称：PAKISTAN VETERINARY JOURNAL （ 影响因子：1.318； 五年影响因子：0.954 ）

ISSN： 0253-8318

年卷期： 2019 年 39 卷 2 期

页码：

收录情况： SCI

摘要： High immune response (HIR) cows have balanced and roborant host defences and lower disease, and selecting young sires is more essential than selecting cows. Foot and mouth disease (FMD) is a communicable disease in cattle, but there is no convenient method for selecting HIR young sires to FMD. In this study, 39 young Holstein sires were vaccinated by a trivalent FMD serotypes (A, O and Asia I) vaccine. Blood samples were obtained from Jugular vein before vaccination and at day 51 after primary vaccination (APV), and antibody levels of the three FMD serotypes, T-cell subsets and routine hematological parameters were detected. HIR and low immune response Holstein young sires were classed by the antibody levels of the three FMD serotypes at day 51 APV. The relation of the antibody levels with the T-cell subsets and routine hematological parameters were analyzed. The results showed that the immune response capability were related to the amounts of CD3(+)CD4(+) and CD3(+)CD8(+) lymphocytes, and the CD4/CD8 ratio was correlated to the antibody titers after vaccination. In conclusion, level of platelet and mid cell count before vaccination, and CD4/CD8 ratio and level of platelet after vaccination may be used to select the HIR young sires. (C) 2019 PVJ. All rights reserved

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[1]Correlation of Antibody Levels with Peripheral Lymphocyte Subsets and Routine Hematological Parameters after Vaccination with FMD Vaccine in Young Sires. Yang, Ling,He, Kaili,He, Kaili,Li, Jianbin,Li, Rongling,Hou, Minghai,Gao, Yundong,Zhong, Jifeng,He, Kaili,Ma, Yabin. 2019

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