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Use of a bovine genome chip to identify new biological pathways for beef quality in cattle

文献类型: 外文期刊

作者: Liu Guifen 1 ; Liu Xiaomu 1 ; Wan Fachun 1 ; Tan Xiuwen 1 ; Cheng Haijian 1 ; Song Enliang 1 ;

作者机构: 1.Shandong Acad Agr Sci, Inst Anim Sci & Vet Med, Jinan 250100, Peoples R China

2.Shandong Key Lab Anim Dis Control & Breeding, Jinan 250100, Peoples R China

关键词: Microarray;Biological pathway;Muscle;Lilu beef cattle

期刊名称:MOLECULAR BIOLOGY REPORTS ( 影响因子:2.316; 五年影响因子:2.357 )

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收录情况: SCI

摘要: The accumulation of muscle is largely influenced by the genetic background of cattle. Muscle tissue was collected from the longissimus muscle of Lilu beef cattle at 12, 18, 24 and 30 months old. Using meat quality analysis, we found that the Lilu beef cattle have good production and slaughter performance, the performance meets the criterion of beef cattle. Microarray analysis was able to identify a total of 4,219 genes that are differentially expressed (P ≤ 0.01) between the two groups of cattle (12 vs 18; 18 vs 24; 24 vs 30). Bioinformatics analysis results suggested that most of the differentially expressed genes are involved in the metabolic pathways and neuroactive ligand–receptor interaction pathways. In the future study that aims to look for genes relating to growth and meat quality, we will focus on the genes that have been shown to have a significant variation between groups and are involved in the two pathways.

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