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Synthesis and Bioactivities of Novel 1,3,4-oxadiazole Derivatives Containing Pyridine Moiety

文献类型: 外文期刊

作者: Sun, Guo-Xiang 1 ; Shi, Yan-Xia 3 ; Sun, Zhao-Hui 2 ; Yang, Ming-Yan 2 ; Wu, Hong-Ke 2 ; Weng, Jian-Quan 2 ; Tan, Cheng-Xia 2 ; Liu, Xing-Hai 2 ; Li, Bao-Ju 3 ; Zhang, Yong-Gang 4 ;

作者机构: 1.Yancheng Inst Technol, Sch Chem & Biol Engn, Yancheng 224051, Jiangsu, Peoples R China

2.Zhejiang Univ Technol, Coll Chem Engn, Hangzhou 310014, Zhejiang, Peoples R China

3.Chinese Acad Agr Sci, Inst Vegetables & Flowers, Beijing 100014, Peoples R China

4.Shandong Acad Sci, Inst Biol, Jinan 250014, Peoples R China

关键词: 1,3,4-oxadiazole; antifungal activity; microwave synthesis; pyridine

期刊名称:LETTERS IN DRUG DESIGN & DISCOVERY ( 影响因子:1.15; 五年影响因子:0.994 )

ISSN: 1570-1808

年卷期: 2014 年 11 卷 9 期

页码:

收录情况: SCI

摘要: In this paper, some novel 1,3,4-oxadiazole derivatives containing 4-pyridyl group were synthesized under microwave assistant condition by multi-step reactions. The structures were characterized by H-1 NMR, MS and elemental analyses. The target compounds were evaluated for their fungicidal activities, and the results indicated that some of the title compounds displayed good antifungal activities.

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