何希君，汉族，1969年10月生，吉林省大安市人，博士，副研究员，动物疫病诊断中心病理学研究组负责人。2007年毕业于日本东京大学，获兽医学博士学位（四年制）；2007～2011先后以日本学术振兴会（JSPS）特别研究员、特任研究员等身份在东京大学和日本国立放射线医学综合研究所工作。2011年5月回国工作。现为中国畜牧兽医学会兽医病理学分会理事，日本毒性病理学会会员，日本兽医病理学会会员，日本毒理学会会员。 研究方向：动物分子病理学/动物免疫病理学

研究方向

所在机构

中国农业科学院哈尔滨兽医研究所

主要成就

近5年发表的主要研究论文： 1. Zhang Y, Zhang Q, Gao Y, He X, Kong H, Jiang Y, Guan Y, Xia X, Shu Y, Kawaoka Y, Bu Z, Chen H. Key molecular factors in HA and PB2 contribute to the efficient transmission of the 2009 H1N1 pandemic influenza virus. J Virol. 2012 Jun 27. [Epub ahead of print] 2. Hu SP, Zhang Z, Liu YG, Tian ZJ, Wu DL, Cai XH, He XJ. Pathogenicity and Distribution of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus in Pigs. Transbound Emerg Dis. 2012 Jul 5.[Epub ahead of print] 3. kaouar L, Endo Y, He XJ, Lee SJ, Jaroensong T, Mochizuki M, Uchida K, Nakayama H, Sasaki N, Nakagawa T. Relationship between NF-κB expression and malignancy of canine mammary gland tumor tissues. J Vet Med Sci. 2012 Jul 4;74(6):713-8.. 4. Urasoko Y, He XJ, Masao T, Kinoshita Y, Edamoto H, Hatayama K, Asano Y, Tamura K, Mochizuki M. Changes in Blood Parameters and the Expression of Coagulation-Related Genes in Lactating Sprague-Dawley Rats. J Am Assoc Lab Anim Sci. 51(2):144-149, 2012. 5. Rodríguez S., Ito T., He XJ, Uchida K, Nakayama H. Resistance of the golden hamster to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-neurotoxicity is not only related with low levels of cerebral monoamine oxidase-B. Exp Toxicol Pathol. 2011 Jul 25. [Epub ahead of print]. 6. Dong M, He XJ, Tulayakule P, Li JY, Dong KS, Manabe N, Nakayama H, Kumagai S. The toxic effects and fate of intravenously administered zearalenone in goats. Toxicon. 55(2-3):523-530, 2010 7. Shibui Y, He XJ, Uchida K, Nakayama H. MPTP-induced neuroblast apoptosis in the subventricular zone is not regulated by dopamine or other monoamine transporters. Neurotoxicology. 30(6):1036-1044, 2009 8. Urasoko Y, He XJ, Ebata T, Kinoshita Y, Kobayashi J, Mochizuki M, Ikeya M. Changes in blood parameters and coagulation-related gene expression in pregnant rats .J Am Assoc Lab Anim Sci. 48:272-278, 2009. 9. He XJ, Nakayama H. Neurogenesis in Neurotoxin-induced animal models of Parkinson’s Disease- A Review of Current Status. J. Toxicol. Pathol. 22: 101-108, 2009 (invited review)　 10. He XJ, Uchida K, Tochitani T, Uetsuka K, Miwa Y, Nakayama H. Spontaneous cutaneous mast cell tumor with lymph node metastasis in a Richardson’s ground squirrel (Spermophilus richardsonii). J. Vet. Diagn. Invest. 21: 156-159, 2009. 11. He XJ, Uetsuka K, Nakayama H. Neural progenitor cells are protected against MPTP by MAO-B inhibitors. Neurotoxicology 29: 1141-1146, 2008. 12. He XJ, Yamauchi H, Uetsuka K, Nakayama H. Neurotoxicity of MPTP to migrating neuroblasts: studies in acute and subacute mouse models of Parkinsons disease. Neurotoxicology 29: 413-420, 2008. 13. He XJ, Yamauchi H, Suzuki K, Ueno M, Nakayama H, Doi K. Gene expression profiles of drug-metabolizing enzymes (DMEs) in rat liver during pregnancy and lactation. Exp. Mol. Pathol. 83: 428-434, 2007. 14. Yamauchi H, Katayama K, Ueno M, He XJ, Mikami T, Uetsuka K, Doi K, Nakayama H. Essential role of p53 in trophoblastic apoptosis induced in the developing rodent placenta by treatment with a DNA-damaging agent. Apoptosis 12: 1743-1754, 2007. 15. He XJ, Nakayama H, Dong M, Yamauchi H, Ueno M, Uetsuka K, Doi K. Evidence of apoptosis in the subventricular zone and rostral migratory stream in the MPTP mouse model of Parkinson Disease. J. Neuropathol. Exp. Neurol. 6: 873-882, 2006.

教育背景

2007年毕业于日本东京大学，获兽医学博士学位（四年制）

发文趋势