Downregulation of protein kinase PKR activation by porcine reproductive and respiratory syndrome virus at its early stage infection

Xiao, Yueqiang; Ma, Zexu; Wang, Rong; Yang, Liping; Nan, Yuchen; Zhang, Yan-Jin; Xiao, Yueqiang; Ma, Zexu; Wang, Rong; Yang, Liping; Nan, Yuchen; Zhang, Yan-Jin; Xiao, Yueqiang; SCI

机构： Univ Maryland, Mol Virol Lab, VA MD Reg Coll Vet Med, 8075 Greenmead Dr, College Pk, MD 20742 USA; Univ Maryland, Maryland Pathogen Res Inst, College Pk, MD 20742 USA; Shandong Acad Ag;

关键词： Protein kinase PKR PKR inhibition Porcine reproductive and respiratory syndrome virus (PRRSV) Pulmonary alveolar macrophages (PAMs) eIF2 alpha Innate immunity