Design, synthesis and preliminary biological studies of pyrrolidine derivatives as Mcl-1 inhibitors

Wan, Yichao; Sun, Feng'e; Chen, Minglu; Hou, Xuben; Fang, Hao; Wang, Junhua; SCI

机构： Shandong Univ, Minist Educ, Sch Pharm, Dept Med Chem,Key Lab Chem Biol, Jinan 250012, Shandong, Peoples R China; Shandong Acad Agr Sci, Inst Agrofood Sci & Technol, Jinan 250100, Shandong, Peoples R China;

关键词： Apoptosis Bcl-2 Mcl-1 Pyrrolidine Anti-tumor